Duke University Medical Science Research Building II
Durham, NC

Located at the northwest corner of the Medical Center campus, the Medical Science Research Building II, a five-story, 170,000-square-foot laboratory, supports Duke University’s medical mission of teaching, research and patient care, and answers the growing need for more research and support space on campus.

Research Facility


The research facility includes a café, office and meeting space on the first floor and three floors of open research laboratories with one floor specifically designed for the Duke Human Vaccine Institute. The new construction was designed by Hillier Architecture from inception to completion. The building’s construction schedule was phased to accommodate an early move-in for the vivarium, located below grade. The remaining floors were phased as well, to customize the laboratory spaces for the researchers and their move schedules.

Material Palette


The use of “Duke stone,” masonry and pre-cast concrete link the building aesthetically to the campus, which employs this massing and materials palette. The major elements of the building include both contrasting as well as complementary materials and forms.